Last updated: May 2026 — Siddons Law Firm tracks active MDLs each month.
The Big Picture
In re: Depo-Provera (Medroxyprogesterone Acetate) Products Liability Litigation (MDL No. 3140) is consolidated in the Northern District of California. The MDL alleges that long-term Depo-Provera contraceptive use significantly increases the risk of meningioma (a typically benign but often surgically aggressive brain or spinal tumor) and that Pfizer failed to adequately warn women.
Recent Developments
- FDA label change. In December 2025 the FDA added a meningioma warning to the Depo-Provera label, providing strong evidence that the manufacturer knew or should have known of the risk.
- Filing pace accelerating. Several thousand cases have now been filed; intake firms are reporting a significant uptick in qualified prospective plaintiffs through 2026.
- Plaintiff Fact Sheet (PFS) finalized. The court approved a standard PFS in early 2026, streamlining intake and making it easier to evaluate cases for early settlement candidates.
- Bellwether process beginning. The court has not yet announced bellwether selection, but the schedule suggests selection in late 2026 with first trials in 2028.
Who Qualifies
Our firm is currently accepting Depo-Provera meningioma cases that meet all of these criteria:
- Received Depo-Provera or Depo-SubQ Provera 104 contraceptive injections for 12 months or longer.
- Diagnosed with intracranial or spinal meningioma after Depo-Provera use.
- Diagnosis confirmed by MRI, CT, or pathology report.
- Statute of limitations has not run in your state of residence (typically 2–3 years from diagnosis or discovery).
What This Means If You Used Depo-Provera
If you received Depo-Provera shots for a year or longer and have been diagnosed with a meningioma, do NOT delay. Discovery-rule statutes of limitations are running from the date you knew (or reasonably should have known) of the connection — and the December 2025 FDA label change is the strongest possible “knew or should have known” trigger date in many states.
Learn more about Depo-Provera meningioma claims →
Or call (610) 255-7500 for a free case review.
Disclaimer: This post summarizes the public status of pending litigation. Nothing in this post is legal advice for any specific claim.
